http://dspace.ewubd.edu:8080/xmlui/handle/123456789/1462 2026-04-23T15:26:16Z http://dspace.ewubd.edu:8080/xmlui/handle/2525/2985 Study on Drug Selling Pattern in Bangladesh Islam, Md. Tanzim In Bangladesh tendency of the mass people to buy medicines without proper prescription. Undoubtedly this is not a healthy practice to adopt. Government published the "Essential Drug List" or "EDL" in 1982 along with the National Drug Policy (NDP). The NDP stated that no medicine of any kind can be manufactured for sale or be imported, distributed or sold unless it is registered with the licensing authority; and no person, being a retailer, is allowed to sell any drug without the personal supervision of a pharmacist registered in any Register of the Pharmacy Council of Bangladesh. Despite substantial progress in drug manufacturing, irrational drug use, inappropriate prescribing, inadequate access to essential drugs, and uncontrolled price are major problems affecting the total health care system badly in Bangladesh. One can get any drugs from anywhere. So in real sense, there is still no 'Prescription Only Drug' in Bangladesh at present. Drug selling pattern is a powerful indicator of rational use of drugs. To find out the picture of Drug Selling Pattern in Bangladesh, a survey program was conducted in three areas namely Dinajpur, Nator and Nowakhali. In case of conducting the program, urban and rural both areas were considered to perform the study. Firstly, the data was collected from those areas with the help of a prepared sample collection form and, then the analysis of the data and finding out the subjected outcomes. The main objective of the study was to improve the drug selling pattern and enhance the rational use of drug to ensure the proper public health. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. 0002-01-01T00:00:00Z http://dspace.ewubd.edu:8080/xmlui/handle/2525/2973 Colorectal Cancer in Bangladesh: Incidence, Factors and Management Islam, Tanhar Colorectal Cancer is one of the most rapidly emerging illnesses in our country and associated with significant morbidity and mortality. In Bangladesh, Colorectal Cancer is an important cause of increasing mortality rate among the adult patients in Bangladesh. In our study of 40 patients, 68% patients were male and 32% patients were female. We observed that 27.5% patients were in age range between 51 and 60 years and 25% patients were between 31 and 40 years of age. A greater prevalence of was observed in male patients rather than in female patients. Among the male and female patients 47% patients are from rural areas and the most frequent risk factors found was Diet having low fruit and vegetable content followed by Polyp in Colon and rectum. We also found that Bloody stool made the main symptom of Colorectal Cancer. We found a variety of treatment pattern to treat the colorectal cancer patients such as Surgery (52.5%), Chemotherapy (40%) and Palliative Chemotherapy for the patients (with Stage-IV Colorectal cancer). Among the Chemotherapeutic agents Oxalitin and Leukovarine were frequently used and percentages for the both drugs were 57.5% and 47.5 respectively. During the treatment period, weakness and Alopecia were found to be the prime side effects having percentage 52.5% and 45% respectively. Among the 40 cases we studied, 25% cases were found to be recurrent. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. 0010-01-01T00:00:00Z http://dspace.ewubd.edu:8080/xmlui/handle/2525/2972 Colorectal Cancer in Bangladesh: Demographic Details, Risk Factors, Diagnosis & Treatment Patterns Hasan, Rasadul Colorectal cancer is the 3m most common cancer in both male & female in the world. Colorectal patients are also increasing in Bangladesh. In our study it was found that out of 31 patients 87.1% were male & 12.9% were female. Most of the patients (32.26%) were in age range between 31-40 years & 83.87% were married. It was observed that 90.32% patients were Muslim & 48.38% were coming from sub-urban area. Most of the patients were s.s.c. or less (41.94%) educated & 58.06% patients were coming from lower middle class family where as 45.16% patients were non-smoker. It was found that Stage I patients were 77.42% & 100% patients had hepatic & renal abnormality. Most of them were loss weights (83.9%) & 61.29% of patients skin color were changed after affecting colorectal cancer. In all case (100%) patients were diagnosis by Digital rectal exam (DRE) , Fecal occult blood test (FOBT), Sigmoidoscopy & Colonoscopy. The most important risk factors were history of ulcerative colotis(28.56%), diet(25%), polyps(l7.86%) etc. The sign and symptoms included decrease appetite (11.15%), feeling of incomplete defecation (11.15%), fever (10.77%), weight loss (10%) etc. The patients were treated with antipsychotic agents (46.1 %), antibiotics (26.6%), antiulcerents (24.8%) & anticancer drugs (5.5%). Anticancer drugs were given only those patients who were in Stage II to Stage IV. In Bangladesh the colorectal cancer diagnosis & treatment patterns are not like as developed countries. For this cause, there are so many patients are died without diagnosis the disease. Illiteracy also helps to increase the death rate. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. 0012-01-01T00:00:00Z http://dspace.ewubd.edu:8080/xmlui/handle/2525/2971 Design and Formulation of In Vitro release of Combined Amlodipine (5mg) and Atenolol (50mg) Tablets and their Comparative Study with other Similar Market Products Rafiq, Zayed The objective of this study is to develop a formulation for an immediate release Amlodipine (Smg) and Atenolol (SOmg) tablet (a monolayer or mixed matrix tablet) and then utilize the correct manufacturing method to bring out the final sample. The combination therapy is useful for the effective treatment of cardiovascular diseases such as hypertension, Angina pectoris, Myocardial infarction. Multi-drug tablets of amlodipine besylate and atenolol were prepared as mono-layer (mixed matrix) tablets containing each drug in a separate layer by using various excipients and processing. After this is complete it is necessary to evaluate the performance of the obtained sample with its competitors that are currently available on the market. This has been done by deducing the % dissolution rate of the sample and then comparing this data with the % dissolution rates of its pharmaceutical competitors. We know that when launching a product onto the market, a lot of research is essential in order to determine whether it should or should not go into the market. This research work is similar to that, although not as extensive and thorough, and aims at determining whether the sample developed is comparable with its existing pharmaceutical competitors. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. 0002-01-01T00:00:00Z