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Determination of Resistance pattern of Gram positive(+) and Gram Negative (-) Microorganisms against Antibiotic Standard Powder

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dc.contributor.author Rahman, Shafkatur
dc.date.accessioned 2016-05-19T10:39:18Z
dc.date.available 2016-05-19T10:39:18Z
dc.date.issued 2/9/2016
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/1715
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. en_US
dc.description.abstract Antibiotic susceptibility is the susceptibility of bacteria to antibiotics. Antibiotic resistance is the ability of microbes to resist the effects of drugs. The main objective of the study was to determine MIC value of Fluoroquinolones, Cephalosporins, Azithromycin and Vancomycin against 7 isolates of E.coli, 5 isolates of Klebsiella, 2 isolates Salmonella typhi of and 1 isolates of Staphyloococcua aureus and Acinetobacter using broth microdilution. At different concentration of drug organisms were added to 96 well microtiter plate. After incubation optical densities were determined by microtiter plate reader and Minnimum Inhibitory Concentration end point was determined. MIC obtained by this study of fluoroquinolones, Azithromycin and Vancomycin were sensitive for different clinical isolates. But Cephalosporin drugs (cephradine and ceftriaxone) had shown resistance to different isolates of gram positive and gram negative bacteria. Ceftriaxone is a 3rd generation cephalosporin drug which showed resistance to many isolates of different organism. So, further study should be carried out for ceftriaxone using other different methods to determine its susceptibility for different microorganism en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00429
dc.title Determination of Resistance pattern of Gram positive(+) and Gram Negative (-) Microorganisms against Antibiotic Standard Powder en_US
dc.type Thesis en_US


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