Abstract:
Myocardial infarction may be the first manifestation of coronary artery disease, or it may
occur, repeatedly, in patients with established disease like High blood serum cholesterol
which is the major risk factor of myocardial infarction. High cholesterol (hypercholesterolemia) can cause the formation and accumulation of
plaque deposits in the arteries. Atherosclerosis can lead to plaque ruptures and blockages
in the arteries, which increase the risk for heart attack, stroke, circulation problems, and death. Long term duration of uncontrolled blood serum cholesterol may cause serious
disorders. High blood serum cholesterol accelerates and exacerbates the occurrence of
arteriosclerosis, increasing the risk of myocardial infarction. High blood cholesterol is associated with markedly increased mortality in the presence of abnormal high density
lipoprotein (HDL), low density lipoprotein (LDL), triglycerides (TG), total cholesterol
"TC) level after acute myocardial infarction and support for aggressive treatment of
coronary risk factors among hypercholesterolemia patients.The study was conducted in the National Institute of Cardiovascular Diseases and
Hospital (NICVD). The data of 60 patients who were suffering from Myocardial
Infarction were included in the study. To find out the relationship between high blood cholesterol and myocardial infarction,
.a control of high blood cholesterol with in normal range by antilipodial drug, we
cooducted a study with 60 MI patients and then evaluate their all medical history,
6a:g:nosis and treatment. Collected all information then evaluated and compared with
ca:h patient. The result of this study also showed that 41.66% MI patients have optimal'range HDL,
43.33% have borderline HDL, 6.66% have HDL, 3.33% have very high HDL, 20% have
aptimal LDL, 46.66% have borderline LDL, 30% have high LDL, 20% have very high LDL 26.66% have optimal TC, 41.66% have borderline TC, 25% have high TC, and 66% have very high TC with myocardial infarction. The results of the study suggest { myocardial infarction is more prominent in patients with hypercholesterolemia.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.