Abstract:
The plant Stereospermum chelonoides has been used for the general promotion of health
and longevity by Asian tribal. It is used as a traditional medicine for the treatment of
various diseases pain, fever, inflammations, asthma, liver disorders etc. The aim of the
present study was to evaluate the analgesic activity of pet-ether extract and methanol
extract of Stereospermum chelonoides. The powdered barks of Stereospermum
chelonoides were extracted with methanol and pet ether. The fraction was used to
evaluate analgesic activities. The analgesic activity was measured by acetic acid induced
writhing method. Methanol fraction and pet ether fraction showed analgesic activity
respectively with 59.53 % inhibition of pain and 55.85% in the P<0.001. The standard
(Indomethacin) showed pain of inhibition by 86.96 %. The results of study clearly
indicate the presence of analgesic properties of methanol and pet-ether extract. The
obtained results provide a support for the use of this plant in traditional medicine and its
further investigation.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.
