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Determination of the Quality Control Parameters of Paracetamol Tablets in Bangladesh Pharma Market

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dc.contributor.author Mosharraf, Zinia
dc.date.accessioned 2014-03-06T03:13:55Z
dc.date.available 2014-03-06T03:13:55Z
dc.date.issued 7/17/2012
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/29
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) of East West University, Dhaka, Bangladesh. en_US
dc.description.abstract Purpose: The purpose of this research work was to determine the physical quality control parameters of five different brands of paracetamol tablets, each containing three different batches obtained from the Bangladesh Pharma Market. Method: Hundred tablets from each batch of each brand were taken from the market and were determined by the quality control parameters including weight variation, hardness, friability and disintegration test. The tablets used were Napa (Beximco Pharmaceuticals Ltd.), Parapyrol (GlaxoSmithKline Bangladesh Ltd), Reset (Incepta Pharmaceuticals Ltd.), Zerin (Jayson Pharmaceuticals Ltd.) and Tamen (Eskayef Bangladesh Ltd.). The tablets were evaluated to check if they comply with the specifications of USP. Result: All the tablets of all the brands met with the specifications of USP except of Batch# 143 of Zerin which did not comply with the acceptable range of ±5 for the percentage weight variation. The range obtained from the test was -9.5 to 11.8%. Hence, only one parameter of Batch# 143 of Zerin did not meet the specification. Further studies are needed to determine the other quality parameters of the product. Conclusion: Various results were obtained from the test and compared with the specification. The tablets met with the specification and, hence, it can be concluded that the tablets had the desired and optimum therapeutic efficacy. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00265
dc.subject Pharmacy en_US
dc.title Determination of the Quality Control Parameters of Paracetamol Tablets in Bangladesh Pharma Market en_US


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